Browsing by Subject "virus genome"

Now showing items 1-5 of 5

    • Article  

      Cellular HIV-1 DNA levels in drug sensitive strains are equivalent to those in drug resistant strains in newly-diagnosed patients in Europe 

      Demetriou, Victoria L.; van de Vijver, D. A. M. C.; Kousiappa, Ioanna; Balotta, Claudia; Clotet, B.; Grossman, Z.; Jørgensen, L. B.; Lepej, S. Z.; Levy, I.; Nielsen, C.; Paraskevis, Dimitrios N.; Poljak, M.; Roman, F.; Ruiz, L.; Schmidt, J. -C; Vandamme, A. -M; van Laethem, K. V.; Vercauteren, J.; Kostrikis, Leontios G. (2010)
      Background HIV-1 genotypic drug resistance is an important threat to the success of antiretroviral therapy and transmitted resistance has reached 9% prevalence in Europe. Studies have demonstrated that HIV-1 DNA load in ...
    • Article  

      Evidence of two distinct subsubtypes within the HIV-1 subtype A radiation 

      Gao, F.; Vidal, N.; Li, Y.; Trask, S. A.; Chen, Y.; Kostrikis, Leontios G.; Ho, David D.; Kim, J.; Oh, M. -D; Choe, K.; Salminen, M.; Robertson, D. L.; Shaw, G. M.; Hahn, B. H.; Peeters, M. (2001)
      Members of HIV-1 group M are responsible for the vast majority of AIDS cases worldwide and have been classified on the basis of their phylogenetic relationships into nine roughly equidistant clades, termed subtypes. Although ...
    • Article  

      Global genetic variation of HIV-1 infection 

      Anastassopoulou, C. G.; Kostrikis, Leontios G. (2006)
      Variability, both at the population (interhost) as well as at the individual (intrahost) level is a key property of HIV that stems mainly from the inherent infidelity of the reverse transcriptase enzyme that the virus uses ...
    • Article  

      The HPV16 oncogenes cause aberrant stem cell mobilization 

      Michael, S.; Lambert, P. F.; Strati, Katerina (2013)
      Human Papilloma Virus related epithelial cancers have been speculated to derive from virus-infected tissue stem cells. Stem cells also are thought to provide a reservoir of latently infected cells that can persist for long ...
    • Article  

      Near-full genome characterization of unclassified hepatitis c virus strains relating to genotypes 1 and 4 

      Demetriou, Victoria L.; Kostrikis, Leontios G. (2011)
      Near-full genome sequences are presented in this report for the first time of unclassified HCV strains amplified using RT-PCR from plasma of patients living in Cyprus. One strain appears to be a unique genotype-1-like ...